ZFIN All Figures, Crouzier <i>et al.</i>, 2022

Crouzier et al., 2022

ZDB-PUB-220210-9
PMID:35138910
Fig. 6

FIGURE SUMMARY

Title: Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models
Authors: Crouzier, L., Danese, A., Yasui, Y., Richard, E.M., Liévens, J.C., Patergnani, S., Couly, S., Diez, C., Denus, M., Cubedo, N., Rossel, M., Thiry, M., Su, T.P., Pinton, P., Maurice, T., Delprat, B.
Source: Full text @ Sci. Transl. Med.

Fig. 6

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EXPRESSION / LABELING:

Genes:	ncs1a ncs1b sigmar1 wfs1a wfs1b
Antibodies:	Ab1-ncs1 Ab1-tmbim4
Fish:	WT wfs1a^{sa11465/sa11465}; wfs1b^{sa16422/sa16422}
Anatomical Term:	whole organism
Stage:	Day 5

Expression / Labeling details

PHENOTYPE:

Fish:	wfs1a^{sa11465/sa11465}; wfs1b^{sa16422/sa16422}
Conditions:	altered light dark cycle, chemical treatment by environment: N-{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl}-N-propylpropan-1-amine hydrochloride altered light dark cycle, chemical treatment by environment: 1-phenyl-1-cyclohexanecarboxylic acid 2-(4-morpholinyl)ethyl ester altered light dark cycle, chemical treatment by environment: 1-phenyl-1-cyclohexanecarboxylic acid 2-(4-morpholinyl)ethyl ester altered light dark cycle
Observed In:	swimming behavior whole organism
Stage:	Day 5

Phenotype details

Acknowledgments

Full text @ Sci. Transl. Med.

Crouzier et al., 2022 ZDB-PUB-220210-9 PMID:35138910

Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models

Crouzier et al., 2022

ZDB-PUB-220210-9
PMID:35138910