FIGURE

Fig. 2

ID

ZDB-FIG-230920-10

Publication

Verwilligen et al., 2023 - Zebrafish as outgroup model to study evolution of scavenger receptor class B type I functions

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Fig. 2

Fig. 2. Deficiency of SCARB1 affects uptake of HDL in the liver (A) Injection of DiO-HDL (3 h post injection)(green) in 3dpf WT and scarb1^−/− zebrafish larvae. Magnification 10× (B) Uptake and (C) quantification of DiO-HDL in livers of 3dpf WT (n_WT = 3) and scarb1^−/− larvae (n_-1nt = 3 and n_+2nt = 3). Quantification was performed by manually counting the HDL uptake (punctae) outside the sinusoids of 3 confocal image depths per zebrafish. Means ± SEM. p < 0.001*** (Student's t-test). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	scarb1^ibl4/ibl4 (AB/TL) scarb1^ibl5/ibl5 (AB/TL)
Observed In:	liver high-density lipoprotein
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Biochimica et biophysica acta. Molecular and cell biology of lipids, 1868(6), Verwilligen, R.A.F., Mulder, L., Araújo, P.M., Carneiro, M., Bussmann, J., Hoekstra, M., Van Eck, M., Zebrafish as outgroup model to study evolution of scavenger receptor class B type I functions, 159308, Copyright (2023) with permission from Elsevier. Full text @ BBA Molecular and Cell Biology of Lipids