FIGURE
Fig. 9
- ID
- ZDB-FIG-230829-27
- Publication
- George et al., 2022 - Zebrafish model of RERE syndrome recapitulates key ophthalmic defects that are rescued by small molecule inhibitor of shh signaling
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Fig. 9
Shh signaling inhibitor HPI-1 rescues the blowout coloboma phenotype in rerea mutant zebrafish embryos. Treatment of rerea mutant zebrafish embryos with HPI-1 (5 μM) reduces the occurrence of coloboma phenotype from 71.3% to 26.3% (Student's t test, P < .05) coloboma in homozygous mutant embryos.
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Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
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| Condition: | |
| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
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