FIGURE

Fig. 2

ID

ZDB-FIG-230428-40

Publication

Crnko et al., 2023 - The circadian clock remains intact, but with dampened hormonal output in heart failure

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

24-hour expression of core clock genes in murine organs. 24-hour (a) Bmal1, (b) Clock, (c) Per1, and (d) Cry2 expression levels in murine heart, and (e, g) Bmal1 and (f, h) Per1 in (e, f) kidneys and (g, h) liver between sham and HF group (N = 3–5 mice/group/ZT; mean ± SEM), normalised against sham ZT1. Statistical significance of cosinor rhythmicity of delta Ct values per group is indicated at the top left graph corner: ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001. Horizontal bar indicates lights-on (=white; ZT0) and lights-off (=black; ZT12) period. Bmal1 = Brain and Muscle ARNT-Like 1; Clock = Circadian Locomotor Output Cycles Kaput; Cry2 = Cryptochrome Circadian Regulator 2; HF = heart failure; Per1 = Period Circadian Regulator 1; ZT = zeitgeber time.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ EBioMedicine