FIGURE

FIGURE 4

ID

ZDB-FIG-221116-16

Publication

Livne et al., 2022 - Generation and characterization of a novel gne Knockout Model in Zebrafish

Other Figures

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FIGURE 4

gne KO results in skeletal muscle defects which appear at 7 dpf. (A) A reduction in muscle birefringence is observed in gne KO larvae at 7 dpf, compared to WT sibling, and correlates to the severity of the phenotype at 8 dpf. (B) Quantification of the mean birefringence revealed a significant reduction in birefringence at 7 dpf, and highly significant at 8 dpf, compared to WT sibling controls (Mann-Whitney Wilcoxon test, n = 60). Significant differences are indicated by *p < 0.05, **p < 0.01, ****p < 0.00001, standard errors are presented.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gne^rm4/rm4
Observed In:	trunk musculature skeletal muscle myofibril
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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