FIGURE
Fig. 3
- ID
- ZDB-FIG-221111-3
- Publication
- Lam et al., 2021 - Identification of a wide spectrum of ciliary gene mutations in nonsyndromic biliary atresia patients implicates ciliary dysfunction as a novel disease mechanism
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Fig. 3
Fig. 3. Knockout of pcnt, kif3b and ttc17 resulted in defective bile flow in mutant zebrafish. (a) Representative epifluorescence images and (b) line plot of pcnt (n = 51), kif3b (n = 55) and ttc17 (n = 56) mutant embryo groups at 5 days post-fertilization showing significantly lower accumulated PED6 integrated density in gallbladder (arrowhead) after incubation for 30 min (left), 1 h (middle) and 2 h (right) compared to wild type (n = 57). Data expressed as mean ± standard error of the mean (SEM). Results of pairwise t-test: ***, P < 0.001; **, P < 0.01, *, P < 0.05. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagents: | |
| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
Acknowledgments
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