FIGURE

Fig. 6

ID

ZDB-FIG-220829-216

Publication

Quelle-Regaldie et al., 2022 - A nop56 Zebrafish Loss-of-Function Model Exhibits a Severe Neurodegenerative Phenotype

Other Figures

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Fig. 6

(A,B) Lateral views of WT (A) and nop56^−/− (B) 3.5 dpf larvae showing malformations in the neuromuscular junctions and the innervation of the trunk myomeres. All images are projections from confocal z-stacks. (A,B) Alpha-tubulin staining (magenta) showing alterations in the distribution of fibers and bundles in the trunk (thin arrows). White thick arrows in (A,B) point to posterior lateral line nerve. (C,D) SV2 (green) staining showing alterations in neuromuscular junction (arrows) and myosepta in nop56^−/− compared to wild type. Asterisk in (B,D) marks the spinal cord. Scale bar: 150 μm.

Expression Data

Antibodies:	Ab-SV2 Ab1-tuba
Fish:	WT nop56^{sa12582/sa12582}
Anatomical Terms:	myoseptum primary motor neuron axon trunk neuromuscular junction
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nop56^{sa12582/sa12582}
Observed In:	myoseptum myotome nerve primary motor neuron axon trunk neuromuscular junction
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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