FIGURE

Fig. 1

ID

ZDB-FIG-220824-72

Publication

Lavorato et al., 2022 - Dichloroacetate improves mitochondrial function, physiology, and morphology in FBXL4 disease models

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Fig. 1

Protein alignment and evolutionary conservation of FBXL proteins in Homo sapiens, D. rerio, and C. elegans. Protein alignment of H. sapiens, D. rerio, and C. elegans (see Supplemental Figure 1 for alignment with other species). The locations of mutations in the zebrafish and C. elegans mutant strains studied are shown: c.813T>A, p.Y271X in zebrafish and g.410_1116del, p.Phe105_Lys308del in C. elegans. Protein alignment of conserved F-box–like domain among H. sapiens, D. rerio, and C. elegans is shown. Percentage homology is shown in gray, and white and black indicate the lowest and highest levels of similarity, respectively.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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