FIGURE

Figure 3

ID

ZDB-FIG-220816-42

Publication

Sertori et al., 2022 - Investigation of the causal etiology in a patient with T-B+NK+ immunodeficiency

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Figure 3

Role of MED14 in Development of Thymic Subpopulations in Zebrafish. The effect of med14 knockdown on cell subpopulations was evaluated at 5 dpf by performing WISH on TLF zebrafish embryos with the indicated probes: lck marks most developing thymocytes, ikaros marks thymic seeding progenitors, tcrd marks γδ lineage progenitors, and foxn1 marks thymic epithelial cells. Blue ovals mark the thymus and frequencies of embryos with the exhibited staining pattern are indicated at the lower left of each image. Data are representative of 3 experiments.

Expression Data

Genes:	foxn1 ikzf1 lck trdc
Fish:	TL TL + MO2-med14
Knockdown Reagent:	MO2-med14
Anatomical Terms:	thymus thymus immature gamma-delta T cell thymus pro-T cell thymus thymic epithelium
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TL + MO2-med14
Knockdown Reagent:	MO2-med14
Observed In:	thymus thymus immature gamma-delta T cell thymus pro-T cell thymus T cell differentiation in thymus thymus thymic epithelium
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Immunol