Figure 12. Representation of two kinetic models for PepT2 transporter
Each configuration represents a state, from I to IV (outside) and from I’ to IV’ (inside). The presteady-state currents arise from the redistribution of the negatively charged transporter between states I’, I and II (blue boxes). The binding of the first external proton to state I accelerates the inward rate constant, while the binding of a second proton to state II leads to state III, effectively slowing down the outward rate. Transitions between I’, I and II are voltage dependent. S represents the binding of the substrate. Modified from Chen et al. (1999) and Sala-Rabanal et al. (2008). [Colour figure can be viewed at wileyonlinelibrary.com]
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ J. Physiol.
Your Input Welcome
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if
additional information is required.
Oops. Something went wrong. Please try again later.