FIGURE

Fig. 4

ID

ZDB-FIG-220701-11

Publication

Lüffe et al., 2022 - Loss-of-Function Models of the Metabotropic Glutamate Receptor Genes Grm8a and Grm8b Display Distinct Behavioral Phenotypes in Zebrafish Larvae (Danio rerio)

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Fig. 4

Grm8a is partly expressed in gad1a positive neurons in the developing zebrafish brain. (A) Whole-mount RNA in situ hybridization of grm8a expression at 36 hpf. (B) Magnified picture of the region boxed in (A). Scale bar, 200 μm (overview) and 100 μm (magnification). (C–T) Double labeling of grm8a (blue) and gad1a (red) expression in 36 hpf old embryos using two-color RNA in situ hybridization. Lateral (C,D) and dorsal (F,G) overview of embryonic CNS with anterior to the left. (E,H) Magnifications of boxed areas in (C,G). Dashed lines in (C,D) indicate cutting sites for cross sections shown in (I–R). (M–P,S,T) Magnifications of boxed areas in (I–L,Q,R), respectively. Arrowheads indicate sites of co-localization. Abbreviations are listed in Table 1. Scale bars: 100 μm (overview), 50 μm (magnified images).

Expression Data

Genes:	gad1a grm8a
Fish:	AB
Anatomical Terms:	caudal tuberculum medulla oblongata preoptic area thalamus ventral telencephalon
Stage:	Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.