FIGURE

Fig. 4

ID

ZDB-FIG-220629-92

Publication

Mu et al., 2022 - Bisphenol analogues induced metabolic effects through eliciting intestinal cell heterogeneous response

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Fig. 4

Fig. 4. 10x single-cell transcriptomic revealed the cell composition of zebrafish intestine of control and bisphenol analogues exposure groups. a t-SNE clustering of total 28,001 single cell transcriptomes with the annotation marks of each cell clusters. b Representative specifically expressed gene of each identified cell cluster. c-f t-SNE clustering of 6401 (c, control), 7698 (d, BPA), 6317 (e, BPAF) and 7585 (f, BPF) single cell transcriptomes colored by significant cell-type clusters. g, Transcriptional changes (log2(expression fold change)) in each identified cell cluster post exposure of three bisphenol analogues exposure. h Changes in the percentage (log2(ratio fold change to control)) of each identified cell cluster post exposure of three bisphenol analogues exposure.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment by environment: bisphenol A chemical treatment by environment: bisphenol AF chemical treatment by environment: bisphenol F
Observed In:	enterocyte intestine macrophage intestine proliferative region
Stage:	Days 45-89

Phenotype Detail

Acknowledgments

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