FIGURE

Fig. 3

ID

ZDB-FIG-220629-91

Publication

Mu et al., 2022 - Bisphenol analogues induced metabolic effects through eliciting intestinal cell heterogeneous response

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Fig. 3

Fig. 3. Bisphenol analogues induced intestinal damage. a AB-PAS staining of zebrafish intestinal sections from control and bisphenol analogues treated groups. Blue dye marked acidic mucus and purple dye marked neutral mucus. b-c, Intestinal mucus level in control and bisphenol analogues treated groups based on the proportion of stained area of acidic mucus (b) and neutral mucus (c). d HE staining of zebrafish intestinal sections from control and bisphenol analogues treated groups. Black arrows marked the injury of intestinal villi post exposure. e Intestinal villus width of zebrafish in control and bisphenol analogues treated groups. f-h, Protein level of three inflammatory cytokines, Il-6 (f), Tnfα (g) and Il-1β (h). Asterisks denote significant differences between treatments and the control (determined by a Dunnett’s post hoc comparison; *, p < 0.05; **, p < 0.01). Error bars indicate the standard deviation. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment by environment: bisphenol A chemical treatment by environment: bisphenol AF chemical treatment by environment: bisphenol F
Observed In:	intestinal villus intestine interleukin-1 beta production intestine interleukin-6 production intestine mucus secretion intestine tumor necrosis factor production
Stage:	Days 45-89

Phenotype Detail

Acknowledgments

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