FIGURE

FIGURE 4

ID

ZDB-FIG-220525-8

Publication

Lu et al., 2022 - Cingulin b Is Required for Zebrafish Lateral Line Development Through Regulation of Mitogen-Activated Protein Kinase and Cellular Senescence Signaling Pathways

Other Figures

All Figure Page

Back to All Figure Page

FIGURE 4

The proliferative cells in the PLL primordium are severely decreased while downregulation of cingulin b. (A–F) Representative images of BrdU positive proliferating cells and DAPI labeled nuclei in the controls (A,C,E) and cingulin b-deficient embryos (B,D,F) at 36 hpf. Red arrows indicate the rosette-shaped cell clusters in the primordium (A). Scale bars mark the 10 μm scale. (G) The quantitative analysis of BrdU index in control (n = 16) and cingulin b-MO embryos (n = 18). Data are shown in mean ± SEM. ****p < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-cgnb
Knockdown Reagent:	MO1-cgnb
Observed In:	posterior lateral line primordium cell population proliferation
Stage:	Prim-25

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.