FIGURE

FIGURE 3

ID

ZDB-FIG-220420-18

Publication

Zheng et al., 2022 - Nexmifa Regulates Axon Morphogenesis in Motor Neurons in Zebrafish

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FIGURE 3

Nexmifa affects motor neuron morphogenesis in nexmifa mutant zebrafish embryos. (A) The schematic for three different primary motoneurons (CaP, MiP, and RoP) in fish. (B) Confocal imaging of primary motor neurons in control and nexmifa mutant groups at 48 and 72 hpf. Scale bar = 100 μm (C) The percentage of embryos with normal PMNs in control and nexmifa mutants at 48 hpf (n = 125 and 240, respectively) and 72 hpf (n = 132 and 235, respectively). (D) Cap length in control and nexmifa mutants at 48 hpf (n = 20 and 31, respectively) and 72 hpf (n = 15 and 28, respectively). (E) Number of branches per 1 mm Cap axon in control and nexmifa mutants at 48 hpf (n = 8 and 10, respectively) and 72 hpf (n = 9 and 12, respectively). Bar represent the mean ± standard deviation (SD). ^**p < 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nexmifa^{zf3749/zf3749}; ml2Tg
Observed In:	CaP motoneuron axon primary motor neuron
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Mol. Neurosci.