FIGURE

Fig. 6.

ID

ZDB-FIG-220305-20

Publication

Baronio et al., 2021 - Abnormal brain development of monoamine oxidase mutant zebrafish and impaired social interaction of heterozygous fish

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Fig. 6.

Social preference of mao^+/− adult fish is impaired. (A) Representation of the apparatus used to study the social behavior of adult mao^+/+ and mao^+/− fish and traces of the swimming pattern from both genotypes. Fish behavior was evaluated during a 10 min video recording session in a home-made social interaction apparatus. The apparatus is physically divided into three chambers and digital zones (distal, social and non-social), which were established with EthoVision XT 13 software. n=8 for each genotype. (B-E) Bar charts showing results on the time spent in each zone [social (B), non-social (C), distal (D) and total (E)]. Compared to their siblings, mao^+/− adult fish did not differ in the time spent closer to the social stimulus, spent less time in the non-social zone and more time in the distal zone. When the time spent in the distal zone and non-social zones was summed, the mao^+/+ fish show a preference for the area closer to the social stimulus, whereas when the same comparison is done with their mao^+/− siblings, no preference is detected. Data are mean±s.e.m. Unpaired, two-tailed Student's t-test was used for statistical analysis. *P<0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mao^sa31732/+
Observed In:	social behavior
Stage:	Adult

Phenotype Detail

Acknowledgments

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