FIGURE

Figure 7

ID

ZDB-FIG-211201-206

Publication

Schmitner et al., 2021 - Differential Responses of Neural Retina Progenitor Populations to Chronic Hyperglycemia

Other Figures

All Figure Page

Back to All Figure Page

Figure 7

Photoreceptors are restored from neurod-expressing progenitors. (a–c) In neurod:GFP transgenics, strong GFP is detected mainly in the INL in controls, and in the INL and ONL of pdx1 mutants (a). In controls, neurod:GFP labeled rod-shaped cells in the ONL were observed. In pdx1^−/− mutants, neurod:GFP labeled rod and cone shaped cells in the ONL in most mutants (b,c, see Table 2). Sections were counterstained with DAPI (blue). A significant increase in GFP positive cells in the INL was detected in pdx1^−/− mutants (d). Box plot extends from 75% to 25%, whiskers showing minimum and maximum, line indicates median, n = 10 controls, 9 pdx1^−/−. Scale bar: 50 µm. (INL, inner nuclear layer; ONL, outer nuclear layer).

Expression Data

Gene:	EGFP
Fish:	nl1Tg pdx1^sa280/sa280; nl1Tg
Anatomical Terms:	retinal inner nuclear layer retinal outer nuclear layer retinal cone cell retinal outer nuclear layer retinal rod cell
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pdx1^sa280/sa280; nl1Tg
Observed In:	retinal inner nuclear layer
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cells