FIGURE

Figure 6

ID
ZDB-FIG-210611-62
Publication
Crouzier et al., 2021 - Loss of Pde6a Induces Rod Outer Segment Shrinkage and Visual Alterations in pde6aQ70X Mutant Zebrafish, a Relevant Model of Retinal Dystrophy
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Figure 6

Analysis of rods in pde6aQ70X zebrafish during development. Representative confocal images of the retina of pde6aWT and pde6aQ70X zebrafish obtained after immunostaining of rods with a Rho4d2 antibody highlighting Rhodopsin (red) at 5 dpf (A) and 21 dpf (B). The nuclei were counterstained with DAPI (blue). Scale bar = 30 μm. (C,D) Quantification of the total area of rod outer segments normalized against the length of the retinal section, based on three independent measurements of larvae per group at 5 dpf (C) and 21 dpf (D). The number of animals is indicated within the columns. ∗p < 0.05, ∗∗p < 0.01.
Expression Data
Gene:
Antibody:
Fish:
Anatomical Term:
Stage Range: Day 5 to Days 21-29

Expression Detail
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
rhoab5-rhoABstandard conditionsDay 5IHC
rhoab5-rhoABstandard conditionsDays 21-29IHC
rhoab5-rhopde6asa14581/sa14581 (AB)standard conditionsDay 5IHC
rhoab5-rhopde6asa14581/sa14581 (AB)standard conditionsDays 21-29IHC
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Antibody Labeling
No data available
Phenotype Data
Fish:
Observed In:
Stage Range: Day 5 to Days 21-29

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol
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