FIGURE

Fig. 2

ID

ZDB-FIG-210317-9

Publication

Smeeton et al., 2021 - Zebrafish Model for Spondylo-Megaepiphyseal-Metaphyseal Dysplasia Reveals Post-Embryonic Roles of Nkx3.2 in the Skeleton

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Fig. 2

nkx3.2 mutant zebrafish develop axial skeletal abnormalities. (A,E) µCT imaging of 60 dpf wild types (A,A′) and nkx3.2ua5011/ua5011 mutants (E,E′) shown with gradient 3D rendering in sagittal (A,E) and dorsal (A′,E′) views. (B-D,F-H) Magnifications of three spinal regions: anterior vertebrae (red box, inclusive of the occiput and Weberian apparatus: B,B′,F,F′), precaudal vertebrae with rib articulations (tan box, white arrows indicate corresponding left and right ribs: C,C′,G,G′), and caudal fin vertebrae (blue box, pink arrow indicates caudal-most vertebra: D,D′,H,H′) shown in 3D (B,C,D,F,G,H) and 2D (B′,C′,D′,F′,G′,H′) slice. Scale bars: 1 mm (A,A′); 0.61 mm (E,E′).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nkx3-2^{ua5011/ua5011}
Observed In:	caudal vertebra neural spine rib
Stage:	Pec-fin

Phenotype Detail

Acknowledgments

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