FIGURE
FIGURE 2
- ID
- ZDB-FIG-201211-7
- Publication
- van Wijk et al., 2020 - Anti-tuberculosis effect of isoniazid scales accurately from zebrafish to humans
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FIGURE 2
Internal isoniazid exposure over time in zebrafish larvae for increasing isoniazid doses. Internal exposure as pmol per larva in homogenate samples (left five panels) or as pmol·μl−1 in blood samples (right panel) is shown on a semi‐logarithmic scale for waterborne doses in the external treatment medium, from 0.5‐ to 10‐fold MIC, as indicated in each graph (MIC = 15 mg·L−1), for a constant treatment period of 50 h. Internal exposure linearly increases with dose, and steady state amounts increase with age, suggesting increased net absorption. Open symbols show observations below LLOQ |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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Full text @ Br. J. Pharmacol.