FIGURE

Figure 1

ID

ZDB-FIG-201003-48

Publication

Knuth et al., 2020 - Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish

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Figure 1

VDD in male 6 mpf zebrafish fed a vitamin D null diet. (A) VDD fish had lower whole body levels of both 25(OH)D3 and 1,25(OH)2D3 than lab diet and VD3 sufficient fish. The limit of quanititation (LOQ) was 8 pmol/g and the limit of detection (LOD) was 3 pmol/g. Data are represented as mean ± SD. (B) VDD livers expressed significantly more cyp27b1 and cyp2r1, and significantly less cy24a1, than vitamin D sufficient livers. Data are represented as mean ± SE. *See also Supplementary Table 2.

Expression Data

Genes:	cyp2r1 cyp24a1 cyp27b1
Fish:	AB
Condition:	nutrient decreased
Anatomical Term:	liver
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	nutrient decreased
Observed In:	liver whole organism calcidiol whole organism calcitriol
Stage:	Adult

Phenotype Detail

Acknowledgments

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