FIGURE

Fig. 6.

ID

ZDB-FIG-200904-7

Publication

Lavergne et al., 2020 - Pancreatic and intestinal endocrine cells in zebrafish share common transcriptomic signatures and regulatory programmes

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Fig. 6.

Increase in the number of cells co-expressing ghrl and mlnl in the pax6b^−/− PECs and EECs. FISH using ghrelin (ghrl, labelled in red) and motilin-like (mlnl, labelled in green) probes on 2.5 dpf (A, B, E, F and I) and 4.5 dpf (C, D, G, H, J) zebrafish larvae. Confocal views of the pancreatic islet (A, B, E, F) and of the gut (C, D, G, H). I, J Overlays of ghrl (I′ and J′) and mlnl (I″ and J″) stainings demonstrating co-labelling with the two probes. A, E, I, I′, and I″ are views of the pancreatic islet from a wild-type larva while B and F are the pancreatic islet from pax6b^−/−. C, G Views of the intestines from wild-type larvae; D, H, J, J′, J″ Views of the gut from a pax6b^−/− larvae. Scale bars: 20 microns for A-F and I panels, 50 microns for G, H and J panels

Expression Data

Genes:	ghrl mlnl
Fish:	AB pax6b^sa86/sa86
Anatomical Terms:	endocrine pancreas enteroendocrine cell
Stage Range:	Pec-fin to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pax6b^sa86/sa86
Observed In:	endocrine pancreas enteroendocrine cell
Stage Range:	Pec-fin to Day 4

Phenotype Detail

Acknowledgments

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