FIGURE

Fig. 8

ID

ZDB-FIG-200514-14

Publication

Koth et al., 2020 - Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration

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Fig. 8

Myh11-positive endocardial cells and thrombocytes retain their double identity. (A-B′) In situ hybridisation for itga2b combined with immunohistochemistry for Citrine and Myh11. Arrowheads indicate Myh11-positive itga2b-positive thrombocytes present in the wild-type wound that are largely missing in the runx1 mutant wound at 7 dpci. (C-D′) In situ hybridisation for itga2b combined with immunohistochemistry for Myh11 with nuclear Dapi staining. Both the endocardium (inset) and thrombocytes (arrowheads) still express Myh11 in the wild-type wound at 14 dpci, while being absent in the mutant wound. v, ventricle; w, wound. Scale bars: 100 μm.

Expression Data

Gene:	itga2b
Antibody:	Ab2-myh11
Fish:	ox1Tg runx1^hg1/hg1; ox1Tg
Condition:	cold damage: cardiac ventricle
Anatomical Terms:	endocardium thrombocyte
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	runx1^hg1/hg1; ox1Tg
Condition:	cold damage: cardiac ventricle
Observed In:	endocardium thrombocyte
Stage:	Adult

Phenotype Detail

Acknowledgments

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