FIGURE

Fig. 3

ID

ZDB-FIG-200424-44

Publication

Guglielmi et al., 2020 - Temporal control of Wnt signaling is required for habenular neuron diversity and brain asymmetry

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Premature activation of Wnt signaling causes a reduction of dHbl neurons. (A-D′) Projections of confocal z-stacks. (A-C′) Dorsal views, anterior is towards top focused onto the diencephalon of (A-D′) embryos at 3 dpf. Nuclei are DAPI labeled (purple). (A,A′) LiCl treatment causes delayed habenular neuron differentiation. (B-C′,E) Markers for (B,B′) dHbl and (C,C′) dHbm neurons are reduced as represented in E. (D,D′) Lateral views of IPN innervation by habenular efferent axons, anterior is leftwards. Treated embryos show vIPN innervation, as represented in F. d, dorsal; Hb, habenula, IPN, interpeduncular nucleus; Tec, optic tectum; v, ventral.

Expression Data

Genes:	kctd8 kctd12.1
Fish:	hd1Tg
Condition:	chemical treatment by environment: lithium chloride
Anatomical Term:	dorsal habenular nucleus
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hd1Tg
Condition:	chemical treatment by environment: lithium chloride
Observed In:	dorsal habenular nucleus dorsal habenular nucleus neuron dorsal habenular nucleus neuron differentiation habenula interpeduncular nucleus tegmentum innervation
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development