FIGURE

Fig. 1

ID

ZDB-FIG-200424-42

Publication

Guglielmi et al., 2020 - Temporal control of Wnt signaling is required for habenular neuron diversity and brain asymmetry

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Fig. 1

Wnt signaling activity in and around the developing habenulae. (A-C,E) Projections of confocal z-stacks, dorsal views, anterior is towards the top focused onto the diencephalon of tg(7xtcf-Xla.Siam:nls-mCherry); tg(flh:GFP); tg(foxD3:GFP) transgenic embryos at stages indicated. Nuclei are blue, Wnt active cells are red and the pineal complex is green. Dotted lines highlight the region of the developing habenulae. (D) Graph shows the number of Wnt-active habenular precursors, which are (F) increased, when Wnt signaling is activated by drug treatments, as indicated. Hb, habenulae; MDO, mid-diencephalic organizer; P, pineal; Tc, telencephalon.

Expression Data

Genes:	EGFP GFP mCherry
Fish:	ia5Tg; u711Tg; zf104Tg
Condition:	chemical treatment by environment: lithium chloride
Anatomical Terms:	diencephalon dorsal region mid diencephalic organizer pineal complex
Stage Range:	26+ somites to Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ia5Tg; u711Tg; zf104Tg
Conditions:	chemical treatment by environment: 6-bromoindirubin-3'-oxime chemical treatment by environment: lithium chloride
Observed In:	diencephalon dorsal region diencephalon Wnt signaling pathway
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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