FIGURE

Fig. S1

ID

ZDB-FIG-200217-5

Publication

Singh et al., 2019 - αKlotho Regulates Age-Associated Vascular Calcification and Lifespan in Zebrafish

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Fig. S1

Phenotypic characterization of zebrafish αklotho and fgf23mutants. (A-F) close-up of an eye with opaque overgrowth in αklotho, and fgf23 mutant females: (A) Tü wildtype strain, (B) αklotho, and (C) fgf23 mutant in Tü background; (D) AB wildtype strain, (E) αklotho, and (F) fgf23mutant in AB background. (G-L) top-view showing eye protrusion in αklotho and fgf23 mutant females: (G) Tü wildtype strain, (H) αklotho, and (I) fgf23 mutant in Tü background; (J) AB wildtype strain, (K) αklotho, and (L)fgf23 mutant in AB background. (M-P) αklotho and fgf23 mutants appear comparable to background controls at 2.5 mpf: (M) wildtype and, (N) αklotho (klΔ5) males in Tü background; (O) wildtype and (P) fgf23 (fgf23Δ11) males in AB background.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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