FIGURE

Figure 1

ID

ZDB-FIG-191230-1497

Publication

Collodet et al., 2019 - AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR

Other Figures

All Figure Page

Back to All Figure Page

Figure 1

AMPK-activation profiles in samples used for transcriptome analyses. A) MEFs WT (AMPKα1α2^+/+) or KO (AMPKα1α2^−/−) were treated with vehicle (DMSO), 2 mM AICAR or 10 µM 991 for 4 h. Cell lysates (20 µg) were subjected to Western blot analysis with the indicated antibodies and a representative blot of n = 3 is shown. B) Hepatocytes were isolated from AMPKα1/α liver-specific KO (AMPKα1α2^−/−) mice and control AMPKα1^lox/lox α2^lox/lox mice littermates (AMPKα1α2^+/+). The plated hepatocytes were treated for 4 h with vehicle (DMSO), 3 µM 991, or 300 µM AICAR. Cell lysates (20 µg) were subjected to Western blot analysis using the indicated antibodies. Images are representative of n = 2.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ FASEB J.