FIGURE

Fig. 3

ID

ZDB-FIG-191126-3

Publication

Park et al., 2019 - 3-ketodihydrosphingosine reductase mutation induces steatosis and hepatic injury in zebrafish

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Fig. 3

Transmission electron microscopy (TEM) imaging of hepatocytes. 8,000x magnification in wild type at 7 dpf (left), kdsr^I105R mutant at 7 dpf with mild phenotype (middle), and kdsr^I105R mutant at 7.5 dpf with severe defect (right) ( A). One of representative mitochondria is outlined with white color. N, nucleus. Normal looking mitochondria and abnormal mitochondria were marked with white and black asterisks, respectively. 20,000x magnification images are shown in ( B). Images shown are representative of 2 other animals. Scale bars = 2 µm (panel A), 0.8 µm (panel B). Lip, lipid drops.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kdsr^{muz106/muz106} (AB/TU)
Observed In:	hepatocyte mitochondrial crista hepatocyte mitochondrion
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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