FIGURE

Figure 4—figure supplement 2.

ID

ZDB-FIG-190723-1067

Publication

Carretero-Ortega et al., 2019 - GIPC proteins negatively modulate Plexind1 signaling during vascular development

Other Figures

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Figure 4—figure supplement 2.

Angiogenesis deficits of <italic>gipc1<sup>skt1</sup></italic> and <italic>gipc2 <sup>skt3/skt4</sup></italic> mutants at 32 hpf.

(A–C) Confocal lateral images of the trunk vasculature (green) of 32 hpf embryos (region dorsal to the yolk extension). Anterior, left; dorsal, up. Scale bars (white horizontal lines), 100 μm. Genotypes indicated on top of each image in yellow font. Angiogenesis deficits are indicated as follows: white asterisks (DLAV gaps), magenta asterisks (truncated Se), white greater/less-than signs (thin Se). In the WT image (A), the vessels are designated with the white font as follows: DLAV (Dorsal Longitudinal Anastomotic Vessel), Se (Segmental Vessel), DA (Dorsal Aorta), and PCV (Posterior Cardinal Vein). Related to Figure 4.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gipc1^skt1/skt1; y1Tg gipc2^skt3/+; gipc2^skt4/+; y1Tg
Observed In:	dorsal longitudinal anastomotic vessel intersegmental vessel trunk vasculature sprouting angiogenesis
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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