FIGURE

Fig. 1

ID
ZDB-FIG-190705-8
Publication
Narboux-Neme et al., 2019 - Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border
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Fig. 1

Early phenotype of Dlx5/6-inactivated zebrafish and mouse.

(A-B) Phenotype of wild type (WT) and dlx5a/6a morphant zebrafish at 48 hpf (n>750 for each condition). (C-D) Phenotype of WT and Dlx5/6-/- mutant mice at E11.5 (n = 6 for each condition). Inactivation of Dlx5/6 in zebrafish and mouse leads to early defect of posterior axis development characterized by curly-shaped tail phenotype in both models (B, D, white arrowheads). In Dlx5/6-/- embryos, the caudal phenotype is associated with defect of brain formation (D, blue arrowhead). Scale bar in B for A-B 100 μm, for C-D 1000 μm.
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage: Long-pec

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One
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