FIGURE
Fig. S1
Fig. S1
Tg(Xla.Tubb:bcl-2) Transgene Successfully Blocks Neuronal Apoptosis in Most CNS Regions. Related to Figure 1. (A and B) Whole mount Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay followed by transverse section showing representative images of apoptotic cells (red) (A) and quantification (B) of apoptotic cells in different CNS regions of 3 dpf WT or Tg(Xla.Tubb:bcl-2) embryos injected with pu.1 morpholino. n = 4 and 3 for WT and Tg(Xla.Tubb:bcl-2) embryos, respectively. Values represent means with SD. ns, P＞0.05; ***, P ≤ 0.001; ****, P ≤ 0.0001. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Protruding-mouth |
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Cell, 46, Wu, S., Xue, R., Hassan, S., Nguyen, T.M.L., Wang, T., Pan, H., Xu, J., Liu, Q., Zhang, W., Wen, Z., Il34-Csf1r Pathway Regulates the Migration and Colonization of Microglial Precursors, 552-563.e4, Copyright (2018) with permission from Elsevier. Full text @ Dev. Cell