FIGURE

Fig. 5

ID

ZDB-FIG-180824-48

Publication

Sturtzel et al., 2018 - FOXF1 Mediates Endothelial Progenitor Functions and Regulates Vascular Sprouting

Other Figures

Fig. 5

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Fig. 5

Downregulation of FOXF1 in zebrafish impairs vascular development. (A–C) Light and confocal microscopic images and quantification (at least 100 embryos per group) of tg(fli1:EGFP) embryos at 48 h post-fertilization injected with control (CoMO) or FoxF1 morpholino (SB-FoxF1-MO). Injection of the FoxF1 morpholino resulted in an impaired formation of the ISVs (white marks), DLAVs (yellow marks), and PLs (blue marks). (D–F) Light and confocal microscopic images and quantification (at least 100 embryos per group) of tg(fli1:EGFP) embryos at 120 h post-fertilization injected with control (CoMO) or FoxF1 morpholino (SB-FoxF1-MO). Injection of the FoxF1 morpholino resulted in an impaired formation of the TD (red marks).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	y1Tg + MO1-foxf1 + MO4-tp53
Knockdown Reagents:	MO1-foxf1 MO4-tp53
Observed In:	dorsal longitudinal anastomotic vessel intersegmental vessel sprouting angiogenesis thoracic duct vascular lymphangioblast
Stage Range:	Long-pec to Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Bioeng Biotechnol