- Title
-
FOXF1 Mediates Endothelial Progenitor Functions and Regulates Vascular Sprouting
- Authors
- Sturtzel, C., Lipnik, K., Hofer-Warbinek, R., Testori, J., Ebner, B., Seigner, J., Qiu, P., Bilban, M., Jandrositz, A., Preisegger, K.H., Untergasser, G., Gunsilius, E., de Martin, R., Kroll, J., Hofer, E.
- Source
- Full text @ Front Bioeng Biotechnol
Downregulation of FOXF1 in zebrafish impairs vascular development. (A–C) Light and confocal microscopic images and quantification (at least 100 embryos per group) of tg(fli1:EGFP) embryos at 48 h post-fertilization injected with control (CoMO) or FoxF1 morpholino (SB-FoxF1-MO). Injection of the FoxF1 morpholino resulted in an impaired formation of the ISVs (white marks), DLAVs (yellow marks), and PLs (blue marks). (D–F) Light and confocal microscopic images and quantification (at least 100 embryos per group) of tg(fli1:EGFP) embryos at 120 h post-fertilization injected with control (CoMO) or FoxF1 morpholino (SB-FoxF1-MO). Injection of the FoxF1 morpholino resulted in an impaired formation of the TD (red marks). |