FIGURE

Fig. 4

ID

ZDB-FIG-180724-60

Publication

Hiscock et al., 2018 - Feedback between tissue packing and neurogenesis in the zebrafish neural tube

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

A nort transgenic reporter for Notch activity. (A) Schematic of the 3.5 kb nort proximal promoter. This region contains four canonical rbpj-K-binding sites. (B) nort mRNA (red) and nort:d2GFP (green) transgene expressed in the same tissues at 30 hpf. (C) nort:d2GFP expression was reduced in a rbpj-k MO-injected 48 hpf hindbrain and spinal cord compared with the p53 MO-injected controls. The morphology of the hindbrain was similar to the controls, whereas the rbpj-k MO-injected spinal cord was curved. (D) Normal expression of nort:d2GFP is found in the lens epithelium. Overexpression of myc-NICD1a in the lens using crystAα:gal4 causes enhanced ectopic nort:d2GFP expression. Myc immunofluorescence colocalizes with upregulated d2GFP at 28 hpf.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development