FIGURE
Fig. 9
- ID
- ZDB-FIG-180620-41
- Publication
- Leacock et al., 2018 - Structure/Function Studies of the α4 Subunit Reveal Evolutionary Loss of a GlyR Subtype Involved in Startle and Escape Responses
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Fig. 9
Embryos injected with α4a-SMO1 and the α4aR278Q mutant embryos fail to exhibit correct escape behavior. (A) Wild-type (control) fish responds to touch by with a C-bend, a turn away from the stimulus and rapid swimming. However, embryos injected with α4a-SMO1 (B) or with mRNA for the GlyR α4aR278Q subunit (C) respond more slowly, and have a pronounced head retraction—similar to a localized beo-like contraction (arrow). Single images were extracted from high-speed movies of α4a-SMO1 morphants and embryos injected with GlyR α4aR278Q subunit mRNA. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Long-pec |
Phenotype Detail
Acknowledgments
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Full text @ Front. Mol. Neurosci.