FIGURE

Fig. S3

ID

ZDB-FIG-180501-37

Publication

Stevenson et al., 2017 - Giantin knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression

Other Figures

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Fig. S3

Figure S3 relating to Figure 5: (A) Ventral jaw element views in 8 months old WT and golgb1^{Q2948X/Q2948X} zebrafish, and (B) in 10-month golgb1^X3078/X3078 mutant and WT zebrafish derived from micro CT images. The relative distance from the anterior most point of the lower jaw to the mid-point between the jaw joints and the width between joints is demarked by the red and green line respectively and the ratio between these is calculated in C and D. (E, F) Ventral isorenders of the (E) WT and (F) golgb1^X3078/X3078 mutants. (G-I) Red and blue patches highlight regions on isosurface renders of CT images used for calculation of BMD from a (G) saggital view of the skull, (H) lateral view of the vertebral column and (I) ventral view of the jaw. (J) Quantification of BMD shows no significant differences between WT and mutants in jaw, saggital, or vertebral measurements. Data were analysed using an unpaired t-test; p value: *= <0.05, mean and standard deviation). Data was taken from between 15 and 30 sections per fish (details in methods).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	golgb1^{bsl077/bsl077} golgb1^{sa11389/sa11389}
Observed In:	cranial skeletal system development skeletal tissue tissue homeostasis ventral mandibular arch
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell Sci.