FIGURE

Fig. 2

ID

ZDB-FIG-180420-18

Publication

Silva et al., 2017 - Transcriptomics reveal an integrative role for maternal thyroid hormones during zebrafish embryogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

MTHs regulate the WNT and NOTCH pathway genes during zebrafish embryogenesis. (A) WISH expression analysis of wnt1. Lateral (upper panel) and dorsal images of the brain (lower panel) in control and MCT8 morphant zebrafish embryos at 25hpf. (B) WISH expression of the WNT1 protein secretion regulator - wls, lateral and dorsal images of the brain and lateral images of the spinal cord in control and MCT8 morphant zebrafish embryos at 25hpf. The red arrows denote wls - expressing cells in the spinal cord. (C) Fluorescent WIHC expression analysis of the NOTCH ligand DeltaA in the hindbrain and spinal cord of control and MCT8 morphant embryos at 25hpf. (D) WISH expression analysis of the NOTCH pathway target gene her2 in control and MCT8 morphant zebrafish embryos at 25hpf. Lateral and dorsal images of the brain (first and second panels) and lateral images of the spinal cord are shown (lower panel). hb-hindbrain; mb-midbrain; nt-notochord. In (A,B,D) the scale bars represent 100 μm. In (C) the scale bars represents 25 μm.

Expression Data

Genes:	dla her2 wls wnt1
Antibody:	Ab1-dla
Fish:	AB AB + MO5-slc16a2
Knockdown Reagent:	MO5-slc16a2
Anatomical Terms:	brain hindbrain midbrain spinal cord
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO5-slc16a2
Knockdown Reagent:	MO5-slc16a2
Observed In:	brain hindbrain midbrain spinal cord
Stage:	Prim-5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.