Gene
her2
- ID
- ZDB-GENE-980526-274
- Name
- hairy-related 2
- Symbol
- her2 Nomenclature History
- Previous Names
-
- Hes5a (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II and neurogenesis. Localizes to chromatin. Is expressed in several structures, including central nervous system; ciliary marginal zone; neural keel; posterior neural rod; and spinal cord neural tube. Orthologous to human HES5 (hes family bHLH transcription factor 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 16 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Hairy and Enhancer of Split/HEY-related | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain | Orange domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B2B4
|
133 | ||||
|
UniProtKB:Q90464
|
108 |
Interactions and Pathways
No data available
Plasmids
No data available