FIGURE

Fig. s5

ID

ZDB-FIG-180320-28

Publication

Kim et al., 2017 - Ottogi Inhibits Wnt/β-catenin Signaling by Regulating Cell Membrane Trafficking of Frizzled8

Other Figures

All Figure Page

Back to All Figure Page

Fig. s5

Expression profile of otg in zebrafish embryos

(A) Semi-quantitative RT-PCR analysis of zebrafish ottogi. β-actin is used as a loading control. ottogi transcript is detected from 4-cell to the prim-5 stages (24 hpf). (B-L) In situ hybridization of zebrafish otg at indicated stages. (B-F) otg is ubiquitously expressed from early cleavage to 10-somite stages. (G) otg expression in brain region is increased at late somitogenesis stage. (H) At 24 hpf, otg transcripts are detected in the brain and proximal convoluted tubule (PCT, inset) of pronephros. (I) At 36 hpf, otg expression persists in the brain and pronephric ducts. (J) Cross section of embryo at panel (I) shows that otg transcripts are detected in anterior pronephric ducts (arrows) at 36 hpf. (K) otg transcripts are detected in the brain, pharyngeal arch (PA), and PCT at 72 hpf. (L) In sagittal section of adult brain, otg transcripts are detected in corpus cerebelli (CCe), dorsal thalamus (DT), griseum centrale (GC), periventricular gray zone of optic tectum (PGZ, layers 1 and 2), and torus longitudinalis (TL). TeO indicates tectum opticum.

Expression Data

Gene:	prr7
Fish:	WT
Anatomical Terms:	brain corpus cerebelli dorsal thalamus griseum centrale periventricular grey zone pharyngeal arch pronephric duct pronephric proximal convoluted tubule torus longitudinalis whole organism
Stage Range:	4-cell to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.