FIGURE
Fig. S7
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- ZDB-FIG-180202-7
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- Joris et al., 2017 - Number of inadvertent RNA targets for morpholino knockdown in Danio rerio is largely underestimated: evidence from the study of Ser/Arg-rich splicing factors
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Fig. S7
Stable loss of srsf2b or srsf9 did not lead to the previously observed morphant developmental defects. The injection of sMOsrsf2b or sMOsrsf9 in corresponding mutants recapitulated the MO-associated phenotypes. A, Injection of sMOsrsf2b in wt and srsf2b-/- led to the same developmental defects including brain oedemas. B, Knock-down of srsf9 in wt and mutants using MOs generated vascular defects and the appearance of oedemas on the body. srsf2b-/- and srsf9-/- mutants were identified among offspring from heterozygous carriers by genotyping. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Full text @ Nucleic Acids Res.