FIGURE

Fig. S4

ID

ZDB-FIG-180126-27

Publication

Matsuoka et al., 2017 - CNS-resident progenitors direct the vascularization of neighboring tissues

Other Figures

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Fig. S4

VTA formation in larvae treated with different small-molecule inhibitors. (A–H) 152 hpf Tg(kdrl:ras-mcherry) larval trunk vasculature after treatment with DMSO (A), SB203580 (B), PF573228 (C), U73122 (D), SL327 (E), SU6656 (F), SH-6 (G), and wortmannin (H) from 80 to 152 hpf. SH-6 and wortmannin treatments significantly inhibited VTA formation (yellow arrows). (Scale bar, 100 µm.) (I) Quantification of the average number of somites with VTAs for the experiments shown in A–H (20 somites examined per animal). Values represent means ± SEM (***P < 0.001 by ANOVA followed by Tukey’s HSD test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	s896Tg
Conditions:	chemical treatment by environment: EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor chemical treatment by environment: wortmannin
Observed In:	vertebral artery
Stage:	Day 6

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA