FIGURE

Fig. 6 S2

ID
ZDB-FIG-171016-28
Publication
Ciarlo et al., 2017 - A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development
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Fig. 6 S2

RTK signaling regulates crestin expression.

(A) Treatment of embryos with Chembridge novel kinase inhibitors at 2 ss decreases crestin expression at 15 ss. (B) Quantification of crestin expression in drug-treated embryos based on the scoring system in (A). The combined results of two independent experiments are shown. **p<0.0005, chi-square test (C) Structures of Chembridge kinase inhibitors. (D) Receptor tyrosine kinase inhibitors that had no effect on crestin expression. Chemicals were tested up to 100 μM.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
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