FIGURE
Fig. S5
- ID
- ZDB-FIG-161129-18
- Publication
- Marro et al., 2016 - Collagen XII Contributes to Epicardial and Connective Tissues in the Zebrafish Heart during Ontogenesis and Regeneration
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Fig. S5
Treatment with 20 µm SB431542 reduces the activity of the TGFβ signaling pathway in injured hearts. (A, B) Immunofluorescence imaging of the control cryoinjured hearts detects the presence of pSmad3-positive cells within the peri-injured mycocardium (Tropomyosin-positive area, red) and fibrotic tissue (encircled by a dashed line). Exposure to the inhibitor of TGFβ signaling (SB431542) markedly reduces the number of pSmad3 immunoreactivity. (C) Quantification of the pSmad3-positive cells shown as the percentage of DAPI-labeled nuclei. N = 6. ** P = 0.002. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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