FIGURE

Fig. 3

ID

ZDB-FIG-160510-16

Publication

Roy et al., 2016 - Zebrafish TARP Cacng2 is required for the expression and normal development of AMPA receptors at excitatory synapses

Other Figures

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Fig. 3

Zebrafish embryos injected with morpholino oligonucleotides show morphological changes compared with uninjected embryos, embryos injected with a standard control morpholino oligonucleotide and morphant embryos co-injected with Cacng2 mRNA (A). (B) Bar graph showing the percentage of embryos exhibiting axial malformations such as curved tails or malformed trunks. (C) Bar graphs showing the percentage of embryos exhibiting pericardial edema [shown by an arrow in (A)]. (D) Bar graphs show the cacng2a cDNA copy number in uninjected (n = 9), cacng2a (n = 10) and cacng2b (n = 9) morphants. (E) Bar graphs show the cDNA copy number of cacng2b in uninjected (n = 9), cacng2a (n = 10) and cacng2b (n = 8) morphants. ^aSignificantly different from uninjected controls (p < 0.05). ^bSignificantly different from morpholino controls (p < 0.05). ^cSignificantly different from Cacng2a morphants (p < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-cacng2a AB + MO1-cacng2b AB + MO1-cacng2a + MO1-cacng2b
Knockdown Reagents:	MO1-cacng2a MO1-cacng2b
Observed In:	heart post-vent region
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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