FIGURE

Fig. 5

ID

ZDB-FIG-160208-11

Publication

Yelin-Bekerman et al., 2015 - Hypocretin neuron-specific transcriptome profiling identifies the sleep modulator Kcnh4a

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Fig. 5

Predicted TFs that regulate the expression of Hcrt-neuron–specific transcripts.

(A) TFs with a p <0.005 and their target Hcrt-neuron–specific genes. For each of these transcription factors, a combined score for each gene is calculated according to all of the predicted binding sites in its promoter. Therefore, a gene with an overrepresented binding site of a TF will have a high score for that TF and a lower p value. (B–C′′) Double fluorescent ISH of hsf1 and immunofluorescence staining of EGFP in hcrt:EGFP adult brain section. Single plane (0.5 µM width) view of the Hcrt-neuron region (C–C′′). Arrows mark representative EGFP and hsf1 co-expressing cell.

Expression Data

Genes:	EGFP hsf1
Fish:	r18Tg
Anatomical Term:	hypothalamus hypocretin-secreting neuron
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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