Fig. 7 S1
- ID
- ZDB-FIG-160205-43
- Publication
- Hesse et al., 2015 - The human ARF tumor suppressor senses blastema activity and suppresses epimorphic tissue regeneration
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The ARF:ARF transgene does not interfere with development, whereas forced ARF expression causes embryonic lethality. (A) Quantification of embryonic mortality at 48 hpf and 72 hpf in wild type (WT) and ARF:ARF embryos (left; N = 90, p>0.05). Representative sagittal confocal images of ARF expression at 24 hpf in WT and ARF:ARF (right). (B) Quantification of embryonic mortality at 48 hpf and 72 hpf in WT and hs:ARF embryos exposed to heat shock (left; N = 90, p<0.001). Representative sagittal confocal images of ARF expression at 27 hpf in WT and hs:ARF embryos 3 hr after a single heat shock (right). Scale bars: 200 µm. Results are shown as mean ± standard deviation . n.s.: not significant. |