FIGURE

Fig. 3

ID

ZDB-FIG-151214-53

Publication

Takeuchi et al., 2015 - LSD1/KDM1A promotes hematopoietic commitment of hemangioblasts through downregulation of Etv2

Other Figures

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Fig. 3

Up-regulation of endothelial markers in lsd1^it627 embryos. (A) Expression of etv2 at the indicated developmental stages in WT or lsd1^it627 embryos. The arrowhead indicates the up-regulation of etv2 in the posterior LPM. (B) Expression of fli1a at 21 hpf in WT or lsd1^it627 embryos. The arrowhead indicates the up-regulation of fli1a in the ICM. (C) Expression of fli1a, flk1, tie1, and biklf at 26 hpf in the trunk region. The blue and red arrows indicate up-regulation of endothelial markers and down-regulation of a hematopoietic marker, respectively, in the hematopoietic region. (Right) Diagram of the hematopoietic and endothelial regions in WT embryos.

Expression Data

Genes:	etsrp fli1 kdrl klf17 tie1
Fish:	AB/TL kdm1a^it627/it627 (AB)
Anatomical Terms:	angioblastic mesenchymal cell anterior lateral plate mesoderm endothelial cell hematopoietic system lateral plate mesoderm posterior lateral plate mesoderm
Stage Range:	1-4 somites to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kdm1a^it627/it627 (AB)
Observed In:	angioblastic mesenchymal cell endothelial cell hematopoietic system posterior lateral plate mesoderm
Stage Range:	5-9 somites to Prim-5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA