FIGURE

Fig. 5

ID

ZDB-FIG-151112-33

Publication

Yao et al., 2015 - Differential regulation of Kit Ligand A (kitlga) expression in the zebrafish ovarian follicle cells - evidence for the existence of a cyclic adenosine 3', 5' monophosphate-mediated binary regulatory system during folliculogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Effects of IGF-I on the expression of kitlga in the presence of db-cAMP (A), forskolin (B), and H89 (C). Cultured zebrafish follicle cells were pretreated with db-cAMP (1.5 mM), forskolin (10 µM), or H89 (10 µM) for 30 min before treatment with IGF-I (50 ng/mL) for 6 h. (D) Interactive effects of the PKA and PI3K-Akt pathways on kitlga expression. Cultured zebrafish follicle cells were treated with H89 (10 µM) and LY294002 (50 µM) alone or in combination for 6 h. The data were normalized to the housekeeping gene ef1a and expressed as a percentage of the control group (mean ± SEM, n = 4). Different letters indicate statistical significance (P < 0.05).

Expression Data

Gene:	kitlga
Fish:	WT
Conditions:	chemical treatment: bucladesine, primary cell culture: ovarian follicle chemical treatment: bucladesine, primary cell culture: ovarian follicle chemical treatment: forskolin, primary cell culture: ovarian follicle chemical treatment: Insulin-like growth factor I, primary cell culture: ovarian follicle chemical treatment: Insulin-like growth factor I, primary cell culture: ovarian follicle
Anatomical Term:	ovarian follicle
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Molecular and Cellular Endocrinology, 402, Yao, K., Ge, W., Differential regulation of Kit Ligand A (kitlga) expression in the zebrafish ovarian follicle cells - evidence for the existence of a cyclic adenosine 3', 5' monophosphate-mediated binary regulatory system during folliculogenesis, 21-31, Copyright (2015) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.