FIGURE

Fig. S7

ID

ZDB-FIG-151106-38

Publication

Ningappa et al., 2015 - The Role of ARF6 in Biliary Atresia

Other Figures

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Fig. S7

Proliferation is not affected in arf6-ATG MO-injected or AG1478-treated larvae at 75 hpf.

(A) Confocal images showing EdU⁺ proliferating cells (gray) and H2B-mCherry⁺ BECs (red) in the liver of control, arf6-ATG MO-injected, or AG1478-treated Tg(Tp1:H2B-mCherry) larvae. For EdU labeling, the larvae were treated with EdU for one hour prior to harvest. Dotted lines outline the liver. Scale bar, 50 µm. (B) Graph showing the total number of BECs in each liver. Asterisks indicate statistical significance: * p<0.0001, ** p<0.005. (C) Graph showing the percentage of EdU⁺ BECs among BECs. Error bars, ± SEM. n indicates the number of larvae examined.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	s939Tg s939Tg + MO1-arf6a,arf6b
Condition:	chemical treatment: tyrphostin AG 1478
Knockdown Reagent:	MO1-arf6a,arf6b
Observed In:	liver and biliary system cell population proliferation
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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