FIGURE

Fig. 4

ID

ZDB-FIG-150924-11

Publication

Seiler et al., 2015 - Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Decreased expression of lymphoid markers in gene-trap mutant embryos.

(A-F) Whole mount RNA in situ hybridization (WISH) of lck in 5 dpf larvae from the lines fcc143 (143) (A-B), agtpbp1^fcc301 (301) (C-D) and eps15L1^fcc436-P1 (436) (E-F). Representative embryos displaying no GFP (A, E) or normal expression of lck (C) are compared to siblings with strong (str) GFP (B, F) or low levels of lck expression (D). In line agtpbp1^fcc301, the GFP expression levels varied, making it difficult to distinguish heterozygous and homozygous carriers. The number of embryos that showed the representative phenotype is indicated in panels C and D.

Expression Data

Gene:	lck
Fish:	agtpbp1^{fcc301Gt/fcc301Gt} eps15l1b^{fcc436p1Gt/fcc436p1Gt} ubap1^{fcc143Gt/fcc143Gt}
Anatomical Term:	thymus
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	agtpbp1^{fcc301Gt/fcc301Gt} eps15l1b^{fcc436p1Gt/fcc436p1Gt} ubap1^{fcc143Gt/fcc143Gt}
Observed In:	thymus
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One